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Many Americans are concerned about vitamin D deficiency, so in a new study, Vitamin D deficiency Dementia, according to a paper published in The American Journal of Clinical Nutrition in April this year.
“Vitamin D is an increasingly increasing hormone precursor [recognized] Elina Hipponen, Principal Investigator and Director of the Australian Center at the University of South Australia, said: For precision health.
“Our study is the first study to investigate the effects of very low levels of vitamin D on the risk of dementia and stroke using powerful genetic analysis among large populations.”
A genetic study supported by the Australian National Council for Health and Medical Research enrolled 294,514 people from the UK Biobank to investigate the association between 25-hydroxyvitamin D and neuroimaging functions associated with dementia and stroke risk. I analyzed the data from people.
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Hyppönen told Fox News that some people always have slightly lower vitamin D status when compared to other people in similar situations based solely on their genes.
Therefore, this study grouped participants with high or low vitamin D levels based on their genes and investigated the risk of developing dementia based on their vitamin D status.
“If there is a real effect of vitamin D on the risk of dementia, this type of genetic analysis should also provide evidence of this, which is exactly what we saw.”
Vitamin D is a nutrient that we get from certain foods, as well as a hormone that our body makes. According to Harvard TH Chan Public Health School, it helps the body absorb calcium and phosphorus, which builds strong bones.
“Vitamin D production in the skin is the main natural source of vitamin D, but exposure to sunlight is limited because we live in areas where winter sunlight is restricted, or because we are in a lot of time. Many people are inadequate because they have been. “According to Harvard’s website.
However, it is difficult to get enough vitamin D in the foods we eat, so according to Harvard University’s School of Public Health, the best way to ensure adequate levels is to take supplements.
The paper states that this is the first study of its kind to show a direct link between dementia and vitamin D deficiency.
According to the National Cancer Institute, the gold standard for demonstrating causality is a randomized clinical trial, where participants are accidentally divided into separate groups to compare treatment outcomes.
“We used genetic design because it is ethically unacceptable to include people with clinical vitamin D deficiency in randomized clinical trials that are left untreated without the necessary treatment,” Hyppönen said. Told Fox News.
This study found that low levels of vitamin D were associated with a decrease in brain volume and an increased risk of stroke.
Some populations pointed out that increasing everyone to “normal” levels of vitamin D can prevent 17% of cases of dementia. This is described as 50 nmol / L. This is the Institute of of Medical Guidelines.
“In addition, it was possible to investigate this type of genetic benefit associated with the risk of dementia when people always have slightly higher vitamin D status than others in similar situations and the levels are very low. “Hyppönen explained to Fox News.
“The results of these analyzes were particularly exciting. We were able to show that vitamin D has a much stronger effect on the risk of dementia and may be limited to people with very low levels. Please help if you are deficient in Vitamin D. ”
According to the Centers for Disease Control and Prevention (CDC), dementia is a collective term for cognitive dysfunction, making daily activities more difficult.
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The CDC estimates that as of 2014, about 5 million adults over the age of 65 have dementia in the United States, but according to a press release, more than 55 million people worldwide have dementia. I am suffering.
This study points out some limitations, including unexplained residual confounding variables, even if they explain some variables that may affect the results.
The study also pointed to technical statistical limitations on how vitamin D was measured, and the findings were diverse because the analysis used to test causality was limited to participants from Caucasian ancestry. It may not be possible to generalize to.
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“If we could change this reality by making sure that none of us had a serious vitamin D deficiency, it would bring even more benefits and change the health and well-being of thousands of people. “Hyppönen said.
“Most of us seem to be okay, but for those who for some reason can’t get enough vitamin D from the sun, diet changes alone may not be enough and supplements may be needed. . ”