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A new Danish study found that outpatients with COVID-19 were at increased risk of being diagnosed with Parkinson’s disease, Alzheimer’s disease, stroke, and bleeding into the brain compared to COVID-19-negative patients. However, most neuropathy was less frequent than after COVID-19, according to a recent study published in Frontiersin Neurology in June of this year, other respiratory infections.
“More than two years after the onset of the COVID-19 pandemic, the exact nature and evolution of the effects of COVID-19 on neuropathy have not been characterized,” said the lead author, Rigshospitalet’s Department of Neurology. Member Dr. Pardis Zarifkar said. A hospital in Copenhagen, Denmark.
“Previous studies have established an association with neurological syndrome, but it is now clear whether COVID-19 also affects the incidence of certain neurological disorders and is different from other respiratory infections. I don’t know where. ”
The study, recently presented at the 8th European Society of Neurology, found that of a total of 919,731 participants, 43,375 were COVID-19 positive and 876,356 were negative for the disease.
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The study used electronic health records covering about 50% of Denmark’s population with an estimated population of 3 million.
This study analyzed people who were positive for COVID-19 and bacterial pneumonia in a hospital-based facility between February 2020 and November 2021, and responded from February 2018 to November 2019. We reviewed influenza patients during the pre-pandemic period.
Of the 43,375 patients who tested positive for COVID-19, 35,362 were outpatients and 8,013 were hospitalized.
Researchers found that outpatients who tested positive for COVID-19 were 3.5 times more likely to be diagnosed with Alzheimer’s disease, 2.6 times more likely to be diagnosed with Parkinson’s disease, and 2.7 times more likely to have ischemic stroke. We found that intracerebral hemorrhage and risk were 4.8 times higher. Intracerebral hemorrhage.
But when researchers compare Relative risk of neuropathy With other respiratory illnesses such as influenza, with one exception, COVID-19-positive patients have an increased risk of most neurological illnesses compared to patients diagnosed with other respiratory illnesses. There was not.
Researchers have found an increased risk of ischemic stroke among COVID-19 inpatients when compared to influenza inpatients.
This study was limited because it did not consider potential confounding variables such as socioeconomics, lifestyle, existing comorbidities, and length of stay.
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The study included a large number of people, but only the COVID-19 test performed at the hospital facility was tested because it was enrolled in the Danish electronic health record system used in the study for analysis. I could only see a subset of the absolute number of individuals. record.
“COVID-19 has an increased risk of ischemic stroke compared to influenza, but reassuringly, most neuropathy is more frequent with COVID-19 than with influenza or community-acquired bacterial pneumonia. It doesn’t seem to be, “the researchers concluded.
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“The frequency of multiple sclerosis, myasthenia gravis, Guillain-Barré syndrome, and narcolepsy did not differ after COVID-19, influenza, and bacterial pneumonia,” the study added.
“These findings help us better understand the long-term effects of COVID-19 on the body and the role of infections in neurodegenerative diseases and stroke,” said Zarifkar.