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Researchers at Baylor University and Stanford University say they have taken an important step towards condensing some of the benefits of exercise into simple tablets.
Researchers Dr. Yong Xu, a professor at Baylor College of Medicine, and Dr. Jonathan Long, an assistant professor of pathology at Stanford, said they have identified molecules that are produced in the blood during exercise and have been successful in reducing food intake and obesity in mice. I am. Baylor College of Medicine.
“Regular exercise has been shown to help weight loss, regulate appetite, and improve metabolic profile, especially for people who are overweight or obese,” Xu said. “If we can understand the mechanism by which exercise causes these benefits, we will be closer to helping many people improve their health.”
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“We wanted to be able to understand how motion works at the molecular level and capture some of its benefits,” Long added. “For example, older people and frail people who do not exercise well may one day benefit from taking medications that help delay osteoporosis, heart disease, or other conditions.”
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A pair of researchers have identified an amino acid called Lac-Phe. According to Baylor, when they fed mice fed a high-fat diet with amino acid doses, they observed a 50% reduction in food intake over the next 12 hours.
Researchers have also found that humans, and even racehorses, produce the same amino acids when subjected to intense physical activity.
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“Our next step involves finding out more about how Lac-Phe mediates its effects in the body, including the brain,” Xu told Baylor. “Our goal is to learn to coordinate this motor pathway for therapeutic intervention.”